Research Scientist I, RNA Capping (Biotech)
The Research Department at New England Biolabs (NEB) invites applications for a Research Scientist focused on mechanistic research on mRNA capping and cap-modifying enzymes and technology development on capped mRNA synthesis. Viral mRNA capping enzymes from Vaccinia virus and Faustovirus are being used in cap incorporation in lab and manufacturing scales. We are continuing our effort to better understand the mechanistic properties of these complex enzymes through mechanistic research and development of assays that can be deployed by the research and manufacturing community. The ideal candidate will thrive in a highly collaborative and intellectually open environment.
Primary Responsibilities:
Design and implement biochemical research on viral mRNA capping enzymes and RNA 5' modifying enzymes
Design and implement the development of capped mRNA synthesis technologies
Develop and implement enzyme assays to address mechanistic questions and assess capped mRNA synthesis technologies
Formulate testable hypotheses based on structural information
Publish and present novel research findings in scientific journals and conferences.
Assist in the supervision of graduate and undergraduate interns.
Required Qualifications and Experience:
Recent Ph.D. in biochemistry or related discipline.
Solid track record in enzyme kinetics and enzyme-ligand interactions research
Experience in assay development and implementation.
Strong organizational skills with the ability to effectively handle multiple projects.
Demonstrated scientific communication in both formal and informal settings.
Proven analytical and problem-solving skills.
Strong work ethic, emphasizing both efficiency and quality of work.
Excellent interpersonal skills with the ability to thrive in a team environment.
Ability to work independently and as part of a multidisciplinary team.
Strong scientific curiosity, integrity, creativity, and self-motivation.
Preferred Qualifications and Experience:
Proficiency with common bioinformatics tools.
High-throughput experimentation design and execution.
Recombinant protein purification techniques.
Molecular cloning techniques.
EEO Statement
New England Biolabs is committed to fostering a diverse and inclusive community; as an EEO/AA employer, New England Biolabs considers applicants for employment without regard to, and does not discriminate on the basis of, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability. More in-depth details of EEO are available here.
Information regarding New England Biolabs commitment to Diversity, Equity and Inclusion can be found here.
New England Biolabs is a participating employer in the Employment Verification (E-Verify) program.
OFCCP's pay transparency policy can be found on OFCCP's website at www.dol.gov/ofccp
If you need an accommodation for any part of the employment process because of a medical condition or disability, please send an email to hr@neb.com or call 978-927-5054 to let us know the nature of your request.
